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The protein co-immunoprecipitates with RNA editing ribonucleoprotein complexes, which suggests that gBP21 contributes its annealing activity to the RNA editing machinery. Three possible modes of action are considered: chaperone function, matchmaker function and product stabilization. Three lines of evidence substantiate this model. Thirdly, gBP21 has a low affinity for double-stranded RNAs, suggesting the release of the annealed reaction product after the hybridization step.

As a consequence, the electrostatic repulsion between the two annealing reactants is reduced favoring the hybridization reaction. RNA editing in kinetoplastid organisms is a processing reaction whereby the sequence of precursor mRNAs pre-mRNAs is post-transcriptionally modified reviewed in 1. As a result, non-translatable primary transcripts are converted into translatable mRNAs, which makes RNA editing an essential reaction pathway for the expression of mitochondrial genes.

The generated sequence alterations are insertions and deletions of exclusively uridylate residues. As trans -acting components the process involves small, metabolically stable mitochondrial transcripts, known as gRNAs 6.

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Sri Lanka. Rajkot , Gujarat , India. Valsad , Gujarat , India.

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By Salman Ashraf Bheriyani. What makes an individual a proud member of his community? One simply has to look around and observe the dedication of the very young, the youth and elderly alike towards the community through their honorary or voluntary services. This spirit of service to the jamat and the Imam of the Time has always been a source of strength for the Ismaili community. Known for its farming community, the town with lush green surroundings, includes many coconut tree plantations, and is famous for a nut-and-onion product that is exported to Punjab and other states.

Among the one thousand members of the jamat who have made the town their home, there is one outstanding individual who merits special mention.

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